GLP-1

Wegovy and Mounjaro in the UK: NHS Eligibility, Private Options, and Cost Guide (2026)

NHS access requires BMI 35+ (or 30+ with comorbidities). Private prescriptions run £150-300/month. Here is the full breakdown.

2026-04-09
10 min read

Key takeaway: Wegovy (semaglutide 2.4mg) and Mounjaro (tirzepatide) are both available in the UK for weight management. NHS access requires BMI 35+ (or 30+ with comorbidities), referral to a Specialist Weight Management Service, and a wait of several months. Private prescriptions are available through online pharmacies and telehealth services for £150-300/month.

NHS Eligibility for Weight Loss Injections

Wegovy (semaglutide 2.4mg/week)

NICE approved Wegovy for weight management in the UK. NHS eligibility:

  • BMI 35 or above, OR
  • BMI 30-34.9 with at least one weight-related comorbidity (type 2 diabetes, hypertension, obstructive sleep apnoea, cardiovascular disease)
  • Referral to a Specialist Weight Management Service (SWMS) is required — you cannot get Wegovy through your GP alone
  • Maximum treatment duration on NHS: 2 years

The rollout has been gradual. Not all NHS trusts have SWMS capacity, and waiting lists can be 3-12 months depending on your area.

Mounjaro (tirzepatide)

Mounjaro received NICE approval for weight management in the UK. It is a dual GIP/GLP-1 receptor agonist — targeting two hormones instead of one. Eligibility criteria mirror Wegovy (BMI 35+ or 30+ with comorbidities). Available doses: 2.5mg, 5mg, 7.5mg, 10mg, 12.5mg, 15mg.

Ozempic vs Wegovy: Same Drug, Different Licence

OzempicWegovy
Active ingredientSemaglutideSemaglutide
Licensed forType 2 diabetesWeight management
Maximum dose2.0 mg/week2.4 mg/week
NHS coverageYes (with diabetes diagnosis)Yes (via SWMS, BMI criteria)
Private for weight lossOff-label, some providers prescribeOn-label, widely available

Private Options in the UK

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Online pharmacy and telehealth services

  • Boots Online Doctor — offers Wegovy through an online consultation. Requires BMI assessment and medical history review.
  • LloydsPharmacy Online — similar to Boots, online assessment and prescription.
  • Manual — men's health telehealth service that includes GLP-1 prescriptions.
  • Numan — similar telehealth model, offers ongoing support and monitoring.
  • Juniper — weight management programme with GLP-1 prescriptions, dietitian support, and health coaching.

Cost comparison (private)

MedicationApprox. monthly cost (private)Notes
Wegovy 0.25mg (starting dose)£150-200Titration dose — lower cost
Wegovy 2.4mg (maintenance)£250-300Full dose
Mounjaro 2.5mg (starting)£150-180Titration dose
Mounjaro 15mg (maximum)£250-300Full dose
Ozempic 0.25mg (off-label)£150-200Off-label for weight loss

The Titration Schedule

Wegovy titration

MonthWeekly dose
Month 10.25 mg
Month 20.5 mg
Month 31.0 mg
Month 41.7 mg
Month 5+2.4 mg (maintenance)

Mounjaro titration

MonthWeekly dose
Month 12.5 mg
Month 25.0 mg
Month 37.5 mg
Month 410 mg
Month 5+12.5 mg or 15 mg

Do not skip titration steps. The most common side effects (nausea, constipation, reduced appetite) are worse when you increase too quickly. If side effects are severe at a new dose, stay at that dose for an extra 2-4 weeks before increasing.

Managing Side Effects

  • Nausea — usually worst in the first 24-72 hours after each dose increase. Eating smaller, more frequent meals helps.
  • Constipation — increase fibre and water intake. Psyllium husk or a gentle osmotic laxative if needed.
  • Reduced appetite — the intended effect, but can be too aggressive initially. Focus on protein-rich foods.
  • Fatigue — common in the first 2-4 weeks as your body adjusts to lower caloric intake.

Tracking Your Protocol

Tracking your dose, weight, and side effects over time helps you and your prescriber make informed decisions about titration speed and dose adjustments. Regimen lets you log each injection, track your weight trend, and monitor side effects — whether you are on Wegovy, Mounjaro, or Ozempic.

Frequently Asked Questions

Track your Wegovy or Mounjaro dose, weight, and side effects with Regimen. Free for one compound.

Regimen is a tracking tool, not a medical service. We do not provide medical advice. Always consult your healthcare professional before starting, changing, or stopping any medication protocol.

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